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In 1998, the German Research Center for Artificial Intelligence (DFKI) launched the "Innovation in the Call Center (ICC)" project in collaboration with AOL. AOL, a leading Internet service provider at the time, made it possible for customers to send error messages by e-mail for the first time. To handle the often ungrammatical requests, DFKI and AOL developed a system that automatically analyzed e-mails and provided suggested answers via an API interface. Despite the promising results, AOL discontinued the project.

However, for the founders of XtraMind, the predecessor of Sematell - Dr. Klaus Netter, Kader Diagne, Eric Landwehr and Sven Schmeier - this was just the beginning. They recognized the potential of the technology and brought XM-Mailminder onto the market. One of the innovations was the patented "pick-up process", which analyzed emails and suggested suitable responses.

As a DFKI spin-off, Sematell benefited from its close connection to research. Supported by investors such as Jörg Anhalt, Nils Walter and Ragner Kruse, Sematell established itself as the first company to use machine learning as a business model. An important milestone was the successful research call from AOL, which underlined the innovative power of automated email processing and contributed to Sematell's success.